Assessing Ge-132 as an antioxidant in organic and water-containing media

AA Vishtorskaya, EA Saverina, VM Pechennikov… - Journal of …, 2018 - Elsevier
… , and by stimulating the activity of radical scavenging enzymes [15]. Our results support
the idea that direct reducing action (electron/hydrogen atom donor) of Ge-132, as well as the …

[HTML][HTML] Organogermanium (Ge-132) suppresses activities of stress enzymes responsible for active oxygen species in monkey liver preparation

T Tezuka, A Higashino, M Akiba… - Advances in Enzyme …, 2017 - scirp.org
Effects of Ge-132 on promotion of superoxide-scavenging enzyme activities in a monkey
liver preparation. (a) superoxide dismutase; (b) catalase. Data represent mean ± sem (n = 3 …

[PDF][PDF] Organogermanium, Ge-132, promotes the clearance of senescent red blood cells via macrophage-mediated phagocyte activation

T Takeda, J Azumi, M Masaki, T Nagasawa, Y Shimada… - Heliyon, 2024 - cell.com
… the gastrointestinal tract is a molecule responsible for scavenging radicals in 464 the large
intestine. … Accelerated RBC senescence as a novel pathologic 519 mechanism of blood stasis …

The role of germanium in diseases: exploring its important biological effects

X Luo, J Sun, D Kong, Y Lei, F Gong, T Zhang… - Journal of Translational …, 2023 - Springer
… There has been increasing interest among researchers in a novel … In the current research,
Ge-132’s electron scavenging activity is … several types of organogermanium compounds with …

Antioxidant activity of Ge-132, a synthetic organic germanium, on cultured mammalian cells

T Wada, T Hanyu, K Nozaki, K Kataoka… - Biological and …, 2018 - jstage.jst.go.jp
… Antioxidant activity of Ge-132 on the bile in rodents was also reported. … the possible effect on
cell proliferation of Ge-132 and its … Electron scavenging activity of Ge-132 was suggested as …

Bioorganic and medicinal organogermanium chemistry

T Nakamura, Y Shimada, K Sato - Organogermanium …, 2023 - Wiley Online Library
… experimental system for Ge-132, so the Ge-132 derivative was … in a book [68], we introduce
Asaigermanium (Ge-132) as a … it exhibits a radical scavenging effect and is metabolized to …

Antioxidative effect of carboxyethylgermanium sesquioxide (Ge-132) on IVM of porcine oocytes and subsequent embryonic development after parthenogenetic …

E Kim, Y Jeon, DY Kim, E Lee, SH Hyun - Theriogenology, 2015 - Elsevier
… We postulate that it is beneficial to scavenge free radicals and … of Ge-132 have been
investigated in the form of a novel … into the role that organogermanium, especially Ge-132, plays in …

Therapeutic effects of organic germanium

S Goodman - Medical hypotheses, 1988 - Elsevier
… A phase I study with Ge-132 was performed with 23 healthy … with an organogermanium
compound, Ge-132. and … and clinical aspects of a novel organic germanium compound

Carboxyethylgermanium sesquioxide (Ge-132) treatment during in vitro culture protects fertilized porcine embryos against oxidative stress induced apoptosis

E Kim, SU Hwang, JD Yoon, EB Jeung… - … of Reproduction and …, 2017 - jstage.jst.go.jp
… and free radicals relatively easy and then scavenge free radicals and … , Ge-132 can interact
with physiological cis-diol compounds, … However, a higher proportion of organogermanium 3-(…

[HTML][HTML] Advances in effect of germanium or germanium compounds on animals—a review

L Li, T Ruan, Y Lyu, B Wu - Journal of biosciences and medicines, 2017 - scirp.org
… In addition, novel organogermanium sulfide compound, … Ge-132 has a significant inhibitory
effect on the occurrence and … able to scavenge reactive oxygen species and prevent reactive